1. Development of biocompatible substrates, through soft lithography techniques, with different gradient stiffness’s and different surface coating for the control of cell motility and adhesion of cancer cells (i.e. glioblastoma)/ healthy cells and bioactive scaffolds to promote cell adhesion, proliferation and differentiation and with particular emphasis on potential applications of such materials in tissue engineering and medicine regenerative.
2. Synthesis of new smart biomaterials, by uptake in living cells of small fluorescent molecules (in collaboration with Dr. G. Barbarella, CNR-ISOF Bologna).
3. Development of new organic/inorganic delivery system for controlled release of active agents, such as drugs and gene.
Strategies and applications for incorporating physical and chemical modifications for functional Cellulose based materials. Barbara Cortese, Ilaria Elena Palamà, Stefania D’Amone, and Giuseppe Gigli. Cellulose and Cellulose Derivatives: Synthesis, Modification, Nanostructure and Applications. HAUPPAUGE NY 11788-3619: Nova Science Publishers, Inc., 2015 – ISBN: 978-1-63483-571-8, Chapter 2: 35 – 65 (Invited chapter).
Mechanical guidance of cell migration. Ilaria Elena Palamà, Stefania D’Amone, Barbara Cortese. Nanomaterials and Regenerative Medicine. IAPC Publishing, Zagreb, Croatia, 2016 – ISBN: 978-953-56942-3-6, Chapter 22: 563 – 580 (Invited chapter)
Cancer Therapy with Silver Nanoparticles. I.E. Palamà, M. Pollini, F. Paladini, G. Accorsi, A. Sannino and G. Gigli. US 4182.3000. 2013 and WO 3000. 2014.
Abstract: A novel approach in cancer therapy based on the cytotoxic effect of silver nanoparticles on cancer cells, without any deleterious effect on normal cells, has been developed.
My First AIRC Grant – Role of Electro/Mechanical cues in the control and guidance of Glioma Progression (MFAG) 2015 n. 16803 (2015-2018)_ Principal Investigator: Barbara Cortese