Nano-Biotechnology

Nano-biotechnology aims at the development of nanotechnology-based tools for biomedical applications. The bottom-up and top-down approaches, typical of nanotechnology, applied to biology and biochemistry lead to the development of nanostructured materials and devices to improve several fields of current biomedical research like Biomolecular Delivery, advanced and high resolution Imaging and Regenerative Medicine. Nanotechnology investigation tools of materials and surfaces applied to biology increase the basic knowledge ofself-assembly of biomolecules (as described in Biointerfaces) and of cellular mechanisms (Cell Biology). In the view of providing “point-of-care” diagnostic toolsand state-of-the–art approaches towards personalized medicine,microscale devicesare developedas described in the sections Lab on Chip and Biosensors & Bioelectronics. Nano-biotechnological applications are supported by the Modeling, Theory and Computation reported in the section Computational Biology.

Biomolecular Delivery

The major goal in designing nanosystems as drug delivery vectors is to control the release of pharmacologically active agents and to achieve the site-specific action of drugs at a therapeutically optimal rate and dosage regimen…

Cell biology

The research activities of this area at the cross-roads of materials science, nanotechnology and cell biology, primarily focusing on how newly-discovered materials and interfacial processes can be developed and used for specific applications…

Imaging

At NANOTEC several high resolution techniques are available for fine imaging of biomolecules, living cells and tissue. Mainly we focus on engineering of high-resolution molecular and semiconductor-based tools for fine fluorescence imaging…

Regenerative medicine

Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the process of replacing, engineering or regenerating cells, tissues or organs to restore or establish normal function…

Lab on chip (LOC)

The Lab on a Chip (LOC) family is wide and multifaced due to the large number of possible applications ranging from the biomedical to the agrifood and environmental fields….

Latest News

  • Scholar-in-Training Award dell’AACR a Marta Cavo

    Lecce, 15/01/2020
    Marta Cavo, ERC-postdoctoral research fellow at the CNR Institute of Nanotechnology in Lecce (ERC-StG INTERCELLMED No., 759959, PI: Dr. Loretta L. del Mercato), have been selected to receive a Scholar-in-Training Award (USD $625). The Scholarship will support her attendance at the Conference on The Evolving Landscape of Cancer Modeling, organized by the American Association for Cancer Research (AACR), to be held on 2-5 March 2020 in San Diego (California), where she will present the work “Quantifying stroma-tumor cell interactions in three-dimensional cell culture systems”. (more…)
  • I° meeting TecnoMed Puglia

    Lecce, 05 dicembre 2019 – Aula Rita Levi Montalcini – CNR NANOTEC Lecce

    Si terrà domani, giovedì 05 dicembre, con inizio alle ore 14.00 presso l’aula Rita Levi Montalcini del Cnr Nanotec, il “I° meeting TecnoMed Puglia: Tecnopolo per la medicina di precisione“. Il meeting mira a fare il punto sulle attività programmate, sullo stato di avanzamento e sugli highlights.

    Puoi scaricare la locandina da qui

  • Jam session Nanotec… note di scienza su scala nanometrica

    Lecce, 27 settembre 2019 – ex monastero degli Olivetani “CAR-T: l’alba di una nuova era”  con: Attilio Guarini (IRCCS Istituto Tumori “Giovanni Paolo II” di Bari)  introduce e modera: Marco Ferrazzoli (Ufficio Stampa CNR Roma) a cura di: Gabriella Zammillo 

    Le CAR-T (Chimeric Antigens Receptor Cells-T) sono cellule modificate in laboratorio a partire dai linfociti T. Rappresentano una nuova strategia di cura che sfrutta il sistema immunitario per combattere alcuni tipi di tumore come linfomi aggressivi a grandi cellule e leucemie linfoblastiche acute a cellule B. Il prof Attilio Guarini, ematologo all’Istituto tumori Giovanni Paolo II di Bari, le definisce la “vis sanatrix naturae della antica medicina salernitana”, trattandosi del potenziamento dell’attività citotossica dei linfociti del paziente opportunamente ingegnerizzati per riconoscere e contrastare alcuni tipi di cellule tumorali.

    (more…)