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Primo Ricercatore CNR

Prof. Stefano Leporatti, PhD, received his Master Degree in Physics at University of Genoa and obtained in 1999 his PhD in Solid State Physics at Max Planck Institute of Colloids and Interface Science with Prof. Dr. Helmuth Mohwald. He conducted advanced research there and worked as Application Engineer @ Digital Instruments/Veeco Metrology Group, Mannheim (Germany). From 2001 to 2006, he has been Research Scientist at the Institute of Medical Physics & Biophysics, Universität Leipzig, Leipzig (Germany). From 2006 to 2008 he has been Senior Researcher ( Associate Professor Equivalent) at the National Nanotechnology Laboratory (NNL) of CNR-INFM in Lecce, Italy (NanoBioMolecular Division of Prof. R. Rinaldi) and, since 2008, he is there NanoCarriers and BioMechanics Group Leader.

Stefano Leporatti published more than 200 Publications (more than 100 in Peer Reviewed papers, 3 book chapters and 3 invited Review) on biophysical nanostructures. Stefano Leporatti is currently leading a group of 2 PhD students, 2 Graduate students and 1 Postdoc. Tutor of several MasterPhD students, Habilitated as Full and Associate Professor for the Italian Universities in Experimental Physics and Physics of Matter Sectors and Referee of several peer-reviewed Journals (ex: ACS Nano, Langmuir or Nanotechnology).

1) S. Leporatti, O. Cavalleri, R. Rolandi, P. Tundo
" Polymeric Separated Phase in Monomolecular Films revealed by Scanning Force Microscopy " Langmuir 10 ( 1994 ) 1334 - 1336.
2) R. Rolandi, S. Dante, A. Gussoni, S. Leporatti, L. Maga, P. Tundo
" Polymerized Monomolecular Films: Microscopic Structure, Viscosity and Photopolymerization Kinetics " Langmuir 11 ( 1995 ) 3119 - 3129.
3) L. Basano, S. Leporatti, P. Ottonello, V. Palestini, R. Rolandi
" Measurements of surface roughness: use of CCD camera to correlate doubly speckle patterns " Applied Optics vol. 34, No 31, 1st Nov. 1995, 7286-7290.
4) G. Caminati, D. Berti, G. Gabrielli, S. Leporatti, R. Rolandi, M. G. Ponzi – Bossi, B. Yang
" Structural characterization of Langmuir-Blodgett films of nickel complexes with amphiphilic compounds " Thin Solid Films vol. 284 - 285, ( 1996 ), 181 - 186.
5) R. Eggenhoffner, A. Tuccio, R. Masini, A. Diaspro, S. Leporatti, R. Rolandi
" Oriented YBa2Cu3O7- thick films grown by cryo-electrophoresis " Superconducting Science and Technology 10 (1997) 142-146.
6) S. Leporatti, S. Akari, F. Bringezu, G. Brezesinski, H. Möhwald
" Triple chain phospholipid monolayers: a scanning force microscopy and grazing incidence X-ray diffraction study " Applied Physics A Material Science & Processing 66, S1245-S1249, Part 2 Suppl. 5th March 1998.
7) C. DeWolf, S. Leporatti, C. Kirsch, R. Klinger, G. Brezesinski
" Phase separation in phosphatidylinositol/phosphatidylcoline mixed monolayers " Chemistry and Physics of Lipids 97 (1999) 129-138.
8) S. Leporatti, F. Bringezu, G. Brezesinski, H. Möhwald
" Condensed Phases of Branched-Chain Phospholipid Monolayers investigated by Scanning Force Microscopy " Langmuir 14 (1998) 7503-7510.
9) S. Leporatti, G. Brezesinski, H. Möhwald
" Separated Phases of Branched-Chain Phospholipid Monolayers revealed by Scanning Force Microscopy " Colloids and Surfaces A 161 (2000) 159-171.
10) A. Holzwarth, S. Leporatti, H. Riegler
" Molecular ordering and domain morphology of molecularly thin triacotane films at SiO2/air interface  " Europhysics Letters 52, (2), 653-659 (2000).
11) Stefano Leporatti, Andreas Voigt , Rita Mitlöhner, Gleb B. Sukhorukov, Edwin Donath, Helmuth Möhwald
" Scanning Force Microscopy Investigation of Polyelectrolyte Nano- and Microcapsules Wall Texture " Langmuir 16, 4059 (2000) (Article awarded by the Color Cover Issue).
12) Igor L. Radchenko, Gleb B. Sukhorukov, Stefano Leporatti, Gennady B. Khomutov, Edwin Donath, Helmuth Möhwald
" Assembly of alternated multicharged-ion/polyelectrolyte layers on colloid particles. Stability of multilayers and encapsulation of macromolecules into polyelectrolyte capsules " J. Coll. Int. Sci. 230, 272 (2000).
13) G. B. Sukhorukov, S. Davis, A .S. Susha, S. Leporatti, E. Donath, J. Hartmann, H. Möhwald
" Hollow polyelectrolytes shells as template for precipitation of inorganic materials in confined geometry " J. Coll. Int. Sci. 247, 251 (2002).
14) R. Georgieva, S. Moya, G. Reichle, S. Leporatti, B. Neu, H. Bäumler, E. Donath, H. Möhwald
" Conductance and capacitance of polyelectrolyte and lipid-polyelectrolyte composite capsules as measured by electrorotation " Langmuir 16,7075-7081 (2000).
15) S. Moya, L. Dähne, A. Voigt, S. Leporatti, E. Donath, H. Möhwald
" Polyelectrolyte Multilayer Capsules Templated on Biological Cells: Core Oxidation influences Layer Chemistry  " Colloids and Surfaces A 183-185, 27-40 (2001).
16) Stefano Leporatti, Changyou Gao, Andreas Voigt, Edwin Donath, Helmuth Möhwald
" Shrinking of Ultrathin Polyelectrolyte Multilayer Capsules upon Annealing: a Confocal Laser Scanning Microscopy (CLSM) and Scanning Force Microscopy (SFM) study " Eur. Phys. J. E 5,13-20 (2001).
17) Changyou Gao, Stefano Leporatti, Edwin Donath, Helmuth Möhwald
" Surface texture of Poly(styrenesulfonate sodium salt) and Poly(diallyldimethyl ammonium chloride) Micron-sized capsules " J. Phys. Chem B 104, 7144-7149 (2000).
18) Changyou Gao, Stefano Leporatti, Sergio Moya, Edwin Donath, Helmuth Möhwald
" Stability and mechanical properties of polyelectrolyte capsules obtained stepwise by assembly of poly(styrenesulfonate sodium salt) and poly(diallyldimethyl ammonium) chloride onto melamine resin particles " Langmuir 17, 11, 3491-3495 (2001).
19) B. Neu, A. Voigt, R. Mitlöner, S. Leporatti, E. Donath, C. Gao, H. Kiesewetter, H. Möhwald, H. J. Meiselman, H. Bäumler
" Biological Cells as Templated for Hollow Microcapsules " J. of Microenc. 18, 3, 385-395 (2001).
20) Lars Dähne, Stefano Leporatti, Edwin Donath, Helmuth Möhwald
" Fabrication of micro reaction cages with tailored properties " J. Am. Chem. Soc. 123, 23, 5431-5436 (2001) (Article published by Journal Permission with color figures without fees in web and printed edition).
21) Andreas Voigt, Norbert Buske, Gleb B. Sukhorukov, Alexei A. Antipov, Stefano Leporatti, Hans Bäumler, Edwin Donath, Helmuth Möhwald
" Novel Polyelectrolyte multilayer micro- and nanocapsules as magnetic carriers  " J. of Magn. & Magn. Mat. 225, 59-66 (2001).
22) A.A. Antipov, G. B. Sukhorukov, S. Leporatti, I.L. Radchenko, E. Donath, H. Möhwald
" Polyelectrolyte Multilayer Capsules Permeability Control " Coll. & Surf. A Vol. 198-200 (18 February), 535-561 (2002).
23) H. Möhwald, H. Lichtenfeld, S. Moya, A. Voigt, G.B. Sukhorukov, S. Leporatti, L. Dähne, A. Antipov, C.Y. Gao, E. Donath
" From polymeric films to nanocapsules " Studies in Surface science and Catalysis 132, Elsevier Science B.V., Y. Iwasa, N. Oyama, H. Kunieda (Eds.) 485-490 (2001).
24) B.-D. Jung, J-D Hong, A. Voigt, S. Leporatti, L. Dähne, E. Donath, H. Möhwald " Photochromic Hollow Shells: Photoisomerization of Azobenzene Polyionen in Solution, in Multilayer Assemblies on Planar and Spherical Surface "Coll. & Surf. A Vol. 198-200 (8th February ) 483-489 (2002).
25) Zhifei Dai, Andreas Voigt, Stefano Leporatti, Edwin Donath, Helmuth Möhwald
" Layer-by-layer Self assembly of Charged Macromolecules and Aqueous Insoluble Low Molecular Weight Species into Capsules " Adv. Mat. 13, 17, 1339-1342 (2001) (Article awarded by the Color Cover Issue).
26) Xiping Qiu, Stefano Leporatti, Edwin Donath, Helmuth Möhwald
" Studies on the drug release properties of polysaccharide multilayers encapsulated ibuprofen microcapsules " Langmuir 17, 5375-5380 (2001). (Article cited and awarded with a colour image in Editor’s Choice, Science vol. 293, August 24th 2001)
27) Z. Dai, H. Zastrow, S. Leporatti, E. Donath, H. Möhwald, B. Peng
“ Synthesis and encapsulation of N,N,N´,N´- Tetrakis[p-di(n-butyl) aminophenyl]-p-benzoquinone-bis(imonium hexafluoroantimonate “ J. Disper. Sci. Technol. 23 (2002) 555-562.
28) Irina Estrela-Lopis, Stefano Leporatti, Sergio Moya, Astrid Brandt, Edwin Donath, Helmut Mohwald
“ SANS Studies of Polyelectrolyte Multilayers on Colloidal Templates “ Langmuir (2002) 18, 7861-7866.
29) H. Möhwald, H. Lichtenfeld, S. Moya, A. Voigt, G. B. Sukhorukov, S. Leporatti, L. Dähne, I. Radtchenko, A. A. Antipov, C. Gao, E. Donath
“ From polymeric films to nanocapsules”. In "Adsorption and aggregation of surfactants in solution ", Marcel Dekker, New York, (Eds. K. L. Mittal, D. O. Shah) 91-104 (2002).
30) Changyou Gao, Stefano Leporatti, Sergio Moya, Edwin Donath, Helmuth Möhwald
" Swelling and Shrinking of Polyelectrolyte Microcapsules in Response to Changes in Temperature and Ionic Strength " Chemistry Eur. J. (2003) vol. 9, Issue 4, 915-920.
31) S. Moya, W. Richter, S. Leporatti, H. Bäumler, E. Donath
“ Freeze-Fracture Electron Microscopy of Lipid Membranes on Colloidal Polyelectrolyte Multilayer Coated Supports ” Biomacromolecules (2003) 4(3), 808-814.
32) Sabine Hiller, Stefano Leporatti, Andreas Schnäckel, Elke Typlt, Edwin Donath
“ Protamine Assembled in Multilayers on Colloidal Particles Can Be Exchanged and Released ” Biomacromolecules (2004), 5, 1580-1587.
33) Stefano Leporatti, Ronny Sczech, Hans Riegler, Stefano Bruzzano, Joachim Storsberg, Fritz Loth, Werner Jaeger, Andre’ Laschewsky, Stephan Eichhorn, Edwin Donath
“ Interaction Forces Between Microspheres and Ultrathin Cellulose Films monitored by Colloidal Probe Microscopy-Effect of Wet Strength Agents ” J. Colloid and Interface Science (2005) vol 281/1, 101-111.
34) Stefano Leporatti, Anja Gerth, Guido Köhler, Bernd Kohlstrunk, Sunna Hauschildt, Edwin Donath
“ Elasticity and Adhesion Force of Resting and Lipopolysaccharide (LPS)-stimulated Macrophages “FEBS Letters vol 580, Issue 2, 450 (2006).
35) G. Koehler, S. E. Moya, S. Leporatti, Ch. Bitterlich, E. Donath
„ Stability and fusion of lipid layers on polyelectrolyte multilayer supports studied by colloidal force spectroscopy ” Eur. Biophys. J. with Biophys. Lett. 36, 4, 337 (2007).
36) Irina Estrela-Lopis, Stefano Leporatti, Elke Typlt, Daniel Clemens, Edwin Donath
„ Small Angle Neutron Scattering Investigations (SANS) of Polyelectrolyte Multilayer Capsules Templated on Human Red Blood Cells ” Langmuir 23, 7209 (2007).
37) M., Fischlechner, U. Reibetanz, M. Zaulig, D. Enderlein, J. Romanova, S. Leporatti, S. Moya, E. Donath
„ Fusion of Enveloped Virus Nanoparticles with Polyelectrolyte-Supported Lipid Membranes for the Design of Bio/Nonbio Interfaces ” Nano Lett. 7(11), 3540 (2007).
38) Stefano Leporatti “ Atomic Force Microscopy in colloidal and biological systems ” Invited Review in “Biomimetics in Biophysics: model Systems, experimental techniques and Computation” (Research Signpost Publisher, Kerala, India, ) pagg. 67-87 ISBN: 978-81-308-0385-2 Editor: José L. Toca-Herrera. (2010).
39) Irina Estrela-Lopis, Stefano Leporatti, Daniel Clemens, Edwin Donath “Polyelectrolyte multilayer hollow capsules studied by small-angle neutron scattering (SANS) “ Soft Matter , 2009, 5, 214–219. (Hot Paper, Editor suggestion).
40) S. Leporatti, D. Vergara, A. Zacheo, V. Vergaro, G. Maruccio, R. Cingolani, R. Rinaldi “Cytomechanical and topological investigation of MCF-7 cells by scanning force microscopy” Nanotechnology 20 (2009) 055103 (6pp) (doi:10.1088/0957-4484/20/5/055103). (Paper of the month, Cover Page Issue and included in Highlights of 2009 collection of Nanotechnology: ).
41) D. Vergara, R. Martignago, S. Leporatti, S. Bonsegna, G. Maruccio, F. De Nuccio, A. Santino, R. Cingolani, G. Nicolardi, M. Maffia, R. Rinaldi "Biomechanical and proteomic analysis of INF-beta-treated astrocytes" Nanotechnology Vol. 20, Iss. 45, 455106 (2009).
42) Ilaria Elena Palamà, Addolorata Maria Luce Coluccia, Antonio della Torre, Viviana Vergaro, Elisabetta Perrone, Roberto Cingolani, Ross Rinaldi and Stefano Leporatti "Multilayered Polyelectrolyte Capsules and Coated Colloids: Cytotoxicity and Uptake by Cancer Cells". Science of Advanced Materials (2010) Vol. 2, No. 2, pp. 138–150. (Part of 2010 Special Issue:"Advanced Materials for Technological and Biomedical Applications")
43) Ilaria E Palamà, Stefano Leporatti, Emanuela de Luca, Nicola Di Renzo, Michele Maffia, Carlo Gambacorti-Passerini, Ross Rinaldi, Giuseppe Gigli, Roberto Cingolani, Addolorata ML Coluccia "IMATINIB-LOADED POLYELECTROLYTE MICROCAPSULES FORSUSTAINED TARGETING OF BCR-ABL+ LEUKEMIA STEM CELLS" Nanomedicine Future Medicine Ltd (2010) 5(3), pp. 419-431.
44) Viviana Vergaro, Elshad Abdullayev, Yuri M. Lvov, Andre Zeitoun, Roberto Cingolani, Ross Rinaldi and Stefano Leporatti "Cytocompatibility and Uptake of Halloysite Clay Nanotubes" Biomacromolecules (2010) 11, pp. 820–826. (Highly Cited Paper, ISI Web of Science: As of September/October 2015, this highly cited paper received enough citations to place it in the top 1% of its academic field based on a highly cited threshold for the field and publication year).
45) Stefania Bonsegna, Simona Bettini, Rosanna Pagano, Antonella Zacheo, Viviana Vergaro, Giovanna Giovinazzo ,Gabriella Caminati, Stefano Leporatti, Ludovico Valli and Angelo Santino "Plant Oil Bodies: Novel Carriers to Deliver Lipophilic Molecules" Appl. Biochem. Biotechnol. 163(6), 792-802 (2011) (DOI 10.1007/s12010-010-9083-0).
46) V. Vergaro, F. Scarlino, C. Bellomo, R. Rinaldi, D. Vergara, M. Maffia, F. Baldassarre, G. Giannelli X. Zhang, Y. M. Lvov and S. Leporatti "Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells" Advanced Drug Delivery Review, (2011) 63, 847-864.
47) Vergaro Viviana, Abdullayev Elshad, Lvov Yuri M. and Leporatti Stefano "Halloysite clay nanotubes: Novel carriers for cancer therapy" ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY , Vol. 241, Meeting Abstract: 395-PMSE, MAR 27 2011.
48) Vergaro Viviana, Zheng Zhiguo, Zhang Xingcai, Lvov Yuri M. and Leporatti Stefano "Nanocarriers for cancer therapy" ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 241, Meeting Abstract: 321-PMSE , MAR 27 2011.
49) D. Vergara, C. Bellomo, X. Zhang,V. Vergaro, A. Tinelli, V. Lorusso, R. Rinaldi, Y. M. Lvov, S. Leporatti, and M. Maffia"Lapatinib/Paclitaxel Polyelectrolyte Nanocapsules for Overcoming Multidrug Resistance in Ovarian Cancer" Nanomedicine: Nanotechnoloogy, Biology and Medicine (NBM), 8, 891-899 (2012).
50) D. Vergara, P. Simeone, D. Toraldo, P. del Boccio, V. Vergaro, S. Leporatti, D. Pieragostino, A. Tinelli, S. De Domenico, S. Alberti, A. Urbani, M. Salzet, A. Santino, and M. Maffia "Resveratrol downregulates Akt/GSK and ERK signalling pathways in OVCAR-3 ovarian cancer cells" Molecular BioSystems 8, 1078-1087 (2012).
51) F. Baldassarre, V. Vergaro, F. Scarlino, F. De Santis, G. Lucarelli, A. della Torre, G. Ciccarella, R. Rinaldi, G. Giannelli, and S. Leporatti "Polyelectrolyte Capsules as Carriers for Growth Factor Inhibitor Delivery to Hepatocellular Carcinoma" Macromol Biosci, 12, 656-665 (2012) DOI: 10.1002/mabi.201100457.
52) V. Vergaro, F. Baldassarre, F. De Santis, , G. Ciccarella, G. Giannelli, and S. Leporatti "TGF-Beta Inhibitor Loaded Polyelectrolyte Multilayers Capsules for Sustained Targeting of Hepatocarcinoma cells" Invited Review Current Pharmaceutical Design 18, 27, 4155-4164 (2012).
53) A. Mazzocca, F. Baldassarre, V. Vergaro, S. Leporatti, G. Ciccarella, S. Antonaci, G. Giannelli "LY2109761-LOADED MICROCAPSULES AS DRUG DELIVERY SYSTEM TO INHIBIT THE TGF-B1 PATHWAY IN HEPATOCELLULAR CARCINOMA" Journal of Hepatology, Vol. 56, Suppl. 2, April 2012, Page S115.
54) Viviana Vergaro, Yuri M. Lvov and Stefano Leporatti "Halloysite Clay Nanotubes for Resveratrol Delivery to Cancer Cells" Macromolec. Biosci. 12, 9 pp. 1265-1271 (2012), DOI: 10.1002/mabi.201200121.
55) Bianco M, Aloisi A, Arima V, Capello M, Ferri-Borgogno S, Novelli F, Leporatti S, Rinaldi R "Quartz Crystal Microbalance with Dissipation (QCM-D) as tool to exploit antigen-antibody interactions in pancreatic ductal adenocarcinoma detection" Biosens. and Bioelectron. 2013, 42, , 646–652.
56) Maria Serena Chiriacò, Elisabetta Primiceri, Anna Grazia Monteduro, Anna Bove, Stefano Leporatti, Michela Capello, Sammy Ferri-Borgogno, Ross Rinaldi, Francesco Novelli, Giuseppe Maruccio "Towards pancreatic cancer diagnosis by EIS biochips" Lab on Chip 2013,13, 730-734.
57) Nunzio Denora, Valentino Laquintana, Antonio Lopalco, Rosa Maria Iacobazzi, Angela Lopedota, Annalisa Cutrignelli, Giuliano Iacobellis, Cosimo Annese, Maria Francesca Cascione, Stefano Leporatti, and Massimo Franco "In vitro targeting and imaging the translocator protein TSPO 18-kDa through G(4)-PAMAM-FITC labeled dendrimers" J. Contr. Rel. 2013, 172, 1111-1125.
58)Giulia Soloperto, Francesco Conversano, Antonio Greco, Ernesto Casciaro Andrea Ragusa, Aime' Lay-Ekuakille, Stefano Leporatti, Sergio Casciaro "Assessment of the Enhancement Potential of Halloysite Nanotubes for Echographic Imaging" proceedings of IEEE MeMeA 2013 conference, pp. 30 -34, 2013.
59) Giulia Soloperto, Francesco Conversano, Antonio Greco, Ernesto Casciaro Andrea Ragusa, Aime' Lay-Ekuakille, Stefano Leporatti, Sergio Casciaro "Multiparametric Evaluation of the Acoustic Behaviour of Halloysite Nanotubes for Medical Echographic Image Enhancement" IEEE Transactions on Instrumentation and Measurement, Vol, 63 Issue: 6 Pag.1423-1430, 2014.
60) Loretta Laureana del Mercato, Marzia Maria Ferraro, Francesca Baldassarre, Serena Mancarella, Valentina Greco, Ross Rinaldi and Stefano Leporatti “Biological Applications of LbL Multilayer Capsules: From Drug Delivery to Sensing” Advances Colloids and Interface Science (Invited Review, Special Issue Helmuth Mohwald) 207 (2014) 139–154.
61) Daniele Vergara,Pasquale Simeone, Dominga Latorre, Cascione Mariafrancesca, Stefano Leporatti, Marco Trerotola, Anna Maria Giudetti, Loredana Capobianco, Paola Lunetti, Antonia Rizzello, Rosaria Rinaldi, Saverio Alberti, Michele Maffia “Proteomics analysis of E-Cadherin knockdown in epithelial breast cancer cells” J. Biotechnology Special Issue EuroBiotech (2015) 22, pag. 3-11.
62) Daniele Vergara,Marzia M Ferraro, Mariafrancesca Cascione, Loretta L del Mercato, Stefano Leporatti; Anna Ferretta, Paola Tanzarella, Consiglia Pacelli, Angelo Santino, Michele Maffia, Cocco Tiziana, Rosaria Rinaldi, Antonio Gaballo “Cytoskeletal alterations and biomechanical properties of parkin- mutant human primary fibroblasts” 2014, Cells Biochemistry and Biophysics (CBBI), (2015) 71(3), Pag. 1395-1404, DOI: 10.1007/s1213-014-0362-1.
63) Nemany Hanafi, Concetta Nobile, Maria Luisa De Giorgi , Ross Rinaldi and Stefano Leporatti “Control of Colloidal CaCO3 suspension by using biodegradable polymers during fabrication” Beni-Suef University Journal of Basic and Applied Sciences. 4 (2015) pag. 60-70; j.bjbas.2015.02.009.

64) Nemany Hanafy, Concetta Nobile, Maria Luisa De Giorgi, Bhavna Ran, Yuan Cao, Ross Rinaldi,Gianluigi Giannelli and Stefano Leporatti “LY2157299-Loaded Carriers Inhibiting Wound Healing in Hepatocellular Carcinoma” Conference: European Biotechnology Congress Location: Lecce, ITALY Date: MAY 15-18, 2014 JOURNAL OF BIOTECHNOLOGY Volume: 185 Supplement: S Pages: S28-S28 Published: SEP 2014 .
65) Giuseppe Ciccarella, Agostina L Capodilupo, Viviana Vergaro, Francesca Baldassarre, Antonio Cardone, Giuseppina A Corrente, Claudia Carlucci, Stefano Leporatti, Paride Papadia, Giuseppe Gigli “Thiophene-based fluorescent probes with low cytotoxicity and high photostability for lysosomes in living cells” BBA-General Subjects (2015), 1850, 3885-392.
66) L. L. del Mercato, S. Leporatti M. M. Ferraro, N. A. Hanafy, R. Rinaldi, W. J. Parak, S. Carregal-Romero “Multilayer Polyelectrolyte Capsules for Sensing and Drug Delivery: Fundamentals and Applications” Copyright © 2018 by Pan Stanford Publishing Pte Ltd
67) Sergio Casciaro, Giulia Soloperto, Francesco Conversano, Ernesto Casciaro, Antonio Greco, Stefano Leporatti, Aimè Lay-Ekuakille, Giuseppe Gigli “Automatic Image Detection of Halloysite Clay Nanotubes as Future Ultrasound Theranostic Agent for Tumoral Cell Targeting and Treatment” Conference Record - IEEE Instrumentation and Measurement Technology Conference 6860878, pp. 927-930.
68) F. Chiriacò, F. Conversano, E.A. Sbenaglia, S. Casciaro, S. Leporatti, A. Lay-Ekuakille “Cytotoxicity Measurements of Halloysite Nanotubes for Nanomedicine Applications” EEE MeMeA 2014 - IEEE International Symposium on Medical Measurements and Applications, Proceedings 68600126.
69) Chiara Dionisi, Nemany A.N. Hanafy, Concetta Nobile, Maria Luisa de Giorgi, Ross Rinaldi, Sergio Casciaro, Yuri M. Lvov and Stefano Leporatti “ Halloysite Clay Nanotubes as Carriers for Curcumin Delivery” IEEE Transactions On Nanotechnology 2016, in press.
70) Nemany Hanafi, Maria Luisa De Giorgi, Concetta Nobile, Mariafrancesca Cascione, Ross Rinaldi and Stefano Leporatti ”CaCO3 rods as chitosan-polygalacturonic acid carriers for bromopyruvic acid delivery ” Science of Advanced Materials (SAM) 8, 514-523 (2016).
71) Serena Mancarella, Valentina Greco, Francesca Baldassarre, Daniele Vergara, Michele Maffia, Stefano Leporatti "Polymer-coated Magnetic Nanopartocles for Curcumin Delivery to Cancer Cells" Macromolecular Bioscience, 2015 15,1365-1374, DOI:10.1002/mabi.201500142. (Awarded by Frontispiece of 102015 Issue)
72) N.A.N. Hanafy, M.L. De Giorgi, C. Nobile, G. Giannelli, A. Quarta, S. Leporatti P0253: Inhibition of glycolysis by using nanolipid bromopyruvic chitosan carrier is a promising tool to prevent HCC invasiveness Journal of Hepatology (2015) 62, S401.
73) Viviana Vergaro, Paride Papadia, Stefano Leporatti, Sandra A De Pascali, Francesco P Fanizzi, Giuseppe Ciccarella "Synthesis of biocompatible polymeric nano-capsules based on calcium carbonate: a potential cisplatin delivery system" J. Inorganic Biochemistry, (2015) 153, 284-292. DOI:10.1016/j.jinorgbio.2015.10.014.
74) Gianluigi Giannelli, Wolfgang Mikulits, Steven Dooley, Isabel Fabregat, Aristidis Moustakas, Peter ten Dijke, Piero Portincasa, Peter Winter, Richard Janssen Stefano Leporatti,Blanca Herrera, Aranzazu Sanchez "The Rationale for Targeting TGF-β in Hepatocellular Carcinoma" European Journal of Clinical Investigation (2016), 46, 349-361. DOI:10.1111/eci.12596.
75) Chiara Dionisi, Nemany A.N. Hanafy, Concetta Nobile, Maria Luisa de Giorgi, Ross Rinaldi, Sergio Casciaro, Yuri M. Lvov and Stefano Leporatti “ Halloysite Clay Nanotubes as Carriers for Curcumin: Characterization and Application ” IEEE Transactions On Nanotechnology 2016,15 (5), 720-724 DOI: 10.1109/TNANO.2016.2524072.
76) Francesco Conversano, Paola Pisani, Ernesto Casciaro, Marco Di Paola, Stefano Leporatti, Roberto Franchini, Alessandra Quarta, Giuseppe Gigli, and Sergio Casciaro “Automatic Echographic Detection of Halloysite Clay Nanotubes in a Low Concentration Range” Nanomaterials 2016, 6,66; DOI:10.3390/nano6040066.
77) Nemany A. Hanafy, Marzia Maria Ferraro, Antonio Gaballo, Luciana Dini, Vittorianna Tasco, Concetta Nobile, Maria Luisa De Giorgi, Sonia Carallo, Ross Rinaldi and Stefano Leporatti “Fabrication and Characterization of ALK1fc-Loaded Fluoro-Magnetic Nanoparticles for inhibiting TGF β1 in Hepatocellular Carcinoma” RSC Advances 2016, 6, 48834 - 48842. DOI: 10.1039/C6RA06345D.
78) Mariafrancesca Cascione, Valeria De Matteis, Ross Rinaldi and Stefano Leporatti "Atomic Force Microscopy combined with Optical Microscopy for Cells Investigation" Special Issue" Scanning probe microscopy in soft matter and life sciences" Microscopy Research and Techniques, 2016, 80 (1), 109-123 (Invited Review). DOI: 10.1002/jemt.22696.
79) Moitza Principe, Simone Borgoni, Maria Francesca Cascione, Michelle Samuel Chattaragada, Sammy Ferri Borgogno, Michela Capello, Jennifer Chapelle, Francesca Di Modugno, Paola Defilippi, Paola Nisticò, Paola Cappello, Stefano Leporatti, Francesco Novelli "Regulation of pancreatic cancer adhesion, migration and invasion by alpha-Enolase (ENO1)" Journal of Hematology & Oncology 2017, in press. DOI: 10.1186/s13045-016-0385-8.
80) Viviana Vergaro, Elisabetta Carata, Francesca Baldassarre, Elisa Panzarini, Luciana Dini, Claudia Carlucci, Stefano Leporatti, Barbara Federica Scremin, Davide Altamura, Cinzia Giannini and Giuseppe Ciccarella “Scalable production of calcite nanocrystals by atomization process: Synthesis, characterisation and biological interactions study” Advanced Powder Technology 28 (2017) 2445-2455. DOI: 10.1016/j.apt.2016.12.018.
81) Stefano Leporatti "Halloysite Clay nanotubes as Nano-Bazookas for Drug Delivery" Polymer International, (Invited Review) 2017, 66, (8), 1111-1118. DOI: 10. 1002/pi. 5347.
83) Nemany A. Hanafy, Alessandra Quarta, Riccardo Di Corato, Luciana Dini, Concetta Nobile, Vittorianna Tasco, Sonia Carallo, Mariafrancesca Cascione, Ross Rinaldi, Isabel Fabregat and Stefano Leporatti Hybrid Polymeric-Protein Nano-Carriers (HPPNC) for Targeted Delivery of TGFβ Inhibitors to Hepatocellular Carcinoma Cells" Journal of Materials Science: Materials in Medicine, (2017) 28:120 DOI 10. 1007/s10856-017-5930-7.

83) Mariafrancesca Cascione, Valeria De Matteis, Chiara Cristina Toma , Paolo Pellegrino, Stefano Leporatti, Rosaria Rinaldi "Morphomechanical and structural changes induced by ROCK inhibitor in breast cancer cells" Experim. Cell Res. 360 (2017) 303-309. DOI: 2017.

84)Mariafrancesca Cascione, Valeria De Matteis, Chiara Cristina Toma , Paolo Pellegrino, Stefano Leporatti, Rosaria Rinaldi "Biomechanical approach to investigate E-cadherin silencing in breast cancer cells" Under Review, 2018.

85) Luca Salvatore, Vito Emanuele Carofiglio, Paolo Stufano, Valentina Bonfrate, Emanuela Calò, Stefania Scarlino, Paola Nitti, Domenico Centrone, Mariafrancesca Cascione, Stefano Leporatti, Alessandro Sannino, Marta Madaghiele "Potential of electrospun poly(3-hydroxybutyrate)/collagen blends for tissue engineering applications" Journal of Healthcare Engineering, Research Article (13 pages), Article ID 6573947, Volume 2018 (2018).

86) Nemany A.N Hanafy, Luciana Dini, Cinzia Citti, Giuseppe Cannazza and Stefano Leporatti "Inhibition of Glycolysis by using MicroNano-Lipid Bromopyruvic Chyitosan Carrier as Promising Tool to Improve Treatment of Hepatocellular Carcinoma ", Nanomaterials,2018, 8(1), 34. DOI: 10.3390/nano8010034.
87) Gaurav Parekh, Yuanyuan Shi, Juanjuan Zheng, Xingcai Zhang, Stefano Leporatti "Nano-Carriers for Targeted Delivery and Biomedical Imaging Enhancement" Therapeutic Delivery (Invited Review), Vol. 9, N.64, 451-468 2018
88) Xingcai Zhang, Juanjuan Zheng, Yuanyuan Shi, and Stefano Leporatti "Anti-cancer Mechanism and LbL Drug Delivery System for Natural Products" submitted, 2018.
89) Nemany Hanafi, Alessandra Quarta, Marzia Maria Ferraro, Luciana Dini, Concetta Nobile, Maria Luisa De Giorgi, Sonia Carallo, Cinzia Citti, Antonio Gaballo, Giuseppe Cannazza, Ross Rinaldi, Gianluigi Giannelli and Stefano Leporatti “Polymeric Nano-micelles as Novel Cargo-Carriers for LY2157299 Cancer Cells Delivery“ Int. J. Mol. Sci. 2018, 19(3), 748; doi:10.3390/ijms19030748.

90) Valeria De Matteis, Mariafrancesca Cascione, Chiara Cristina Toma and Stefano Leporatti "Morphomechanical and organelles perturbation induced by silver nanoparticles
exposure" J. Nanopart. Res.(2018) 20:273

91) Nemany A.N. Hanafy, Maged Elkemary and Stefano Leporatti "Integration of TGF-β inhibitors inside carrier moieties is a promising way for healthy cells protection", submitted 2018.

92) Valeria De Matteis, Mariafrancesca Cascione, Chiara Cristina Toma and Stefano Leporatti "Silver nanoparticles: synthetic routes, in vitro toxicity and theranostic applications for cancer disease" Nanomaterials 2018, 8, 319. doi:10.3390/nano8050319.

93) Mariafrancesca Cascione, Stefano Leporatti, Francesco Dituri, Gianluigi Giannelli "Transforming growth factor-β promotes morphomechanical effects involved in epithelial to mesenchymal transition in living hepatocellular carcinoma", Intern. J. Molec. Sci. 2019, 20, 108; doi:10.3390/ijms20010108.

94) Mariafrancesca Cascione, Valeria De Matteis, Chiara Cristina Toma, Stefano Leporatti "Morphomechanical alterations induced by transforming growth factor-β1 in epithelial breast cancer cells " Cancers, 2018, 10, 234; doi:10.3390/cancers10070234.

95) Nemany A.N. Hanafy, Maged Elkemary and Stefano Leporatti "Micelles Structure Development as a Strategy to
Improve Smart Cancer Therapy" Cancers 2018, 10, 238; doi:10.3390/cancers10070238.
96) Nemany A.N. Hanafy, Maged Elkemary and Stefano Leporatti "Optimizing CaCO3 matrix might allow to raise their potential use in biomedical application" J Nanosci. Curr. Res. 2018, 3:2
DOI: 10.4172/2572-0813.1000124.
97) Nemany A.N. Hanafy, Maged Elkemary and Stefano Leporatti "Understanding TGF β1 signalling pathway is well strategy to use its encapsulated antagonist as nano therapeutic molecules" J. Translational Science, (2018), 5(4)1-2,DOI:10.15761/JTS.1000264 . 98) Nemany A.N. Hanafy, Maged Elkemary and Stefano Leporatti " Diameter reduction of CaCO3 crystals by using poly acrylic acid might improve cellular uptake of encapsulated curcumin in breast cancer cells" J. Nanomedicine Research, 2018;7(4):235-239, DOI:10.15406/jnmr.2018.07.00193.
99) Stefano Leporatti "Halloysite clay nanotubes as nano-bazookas for drug delivery" ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, MAR 18 2018, 255, 156.
100) Mengxue Zhou, Xingcai Zhang, Jin Xie, Rongxiang Qi, Huiru Lu, Stefano Leporatti, Jun Chen, Yi Hu "pH-sensitive poly(β-amino ester)s nanocarriers facilitate the inhibition of drug resistance in breast cancer cells" Nanomaterials 2018, 8, 952; doi:10.3390/nano8110952.
101) Stefano Leporatti (Ed.) "Nanocolloids for Nanomedicine and Drug Delivery" Pages: 272, Published: December 2018 (This book is a printed edition of the Special Issue Nanocolloids for Nanomedicine and Drug Delivery that was published in Nanomaterials)
102) Nemany A.N. Hanafy, Stefano Leporatti and Maged Elkemary
"Mucoadhesive Hydrogel Nanoparticles as Smart Biomedical Drug Delivery System" Appl. Sci. 2019, 9, 825; doi:10.3390/app9050825.

103)ShuangZhao, FrankCaruso, LarsDaḧne, Gero Decher, BrunoG.De Geest, Jinchen Fan, Neus Feliu, Yury Gogotsi, Paula T. Hammond, Mark C. Hersam, Ali Khademhosseini, Nicholas Kotov, Stefano Leporatti, Yan Li, Fred Lisdat, Luis M. Liz-Marzań, Sergio Moya, Paul Mulvaney, Andrey L. Rogach, Sathi Roy, Dmitry G. Shchukin, Andre G. Skirtach, Molly M. Stevens, Gleb B. Sukhorukov, Paul S. Weiss, Zhao Yue, Dingcheng Zhu, and Wolfgang J. Parak "The Future of Layer-by-Layer Assembly: A Tribute to ACS Nano Associate Editor Helmuth
Möhwald" ACS Nano 2019, 1366, 151-6169.DOI: 10.1021/acsnano.9b03326.104) Fatma Sami El-banna, Magdy Elsayed Mahfouz, Stefano Leporatti, Maged El-Kemary
and Nemany A. N. Hanafy "Chitosan as a Natural Copolymer with Unique Properties for the Development of Hydrogels" Appl. Sci. 2019, 9, 2193; doi:10.3390/app9112193. 105)Valeria De Matteis, Mariafrancesca Cascione, Maria Luisa De Giorgi, Stefano Leporatti and Rosaria Rinaldi "Encapsulation of Thermo-Sensitive Lauric Acid in Silica Shell: A Green Derivate for Chemo-Thermal Therapy in Breast Cancer Cell" Molecules 2019, 24, 2034; doi:10.3390/molecules24112034. 106) Mariafrancesca Cascione, Valeria De Matteis , Giacomo Mandriota, Stefano Leporatti and Rosaria Rinaldi "Acute Cytotoxic Effects on Morphology and Mechanical Behavior in MCF-7 Induced by TiO2NPs Exposure" Int. J. Mol. Sci. 2019, 20, 3594; doi:10.3390/ijms20143594. 107) Jagoba Iturri, Andreas Weber, Alberto Moreno-Cencerrado, Maria dM Vivanco , Rafael Benitez, Stefano Leporatti, and Jose Luis Toca-Herrera "Resveratrol-Induced Temporal Variation in the Mechanical Properties of MCF-7 Breast Cancer Cells Investigated by Atomic Force Microscopy" Int. J. Mol. Sci. 2019, 20, 3275; doi: 10. 3390/ijms20133275.
108) Serena Mancarella, Silke Krol, Alberto Crovace, Stefano Leporatti, Francesco Dituri, Martina Frusciante and Gianluigi Giannelli "Validation of Hepatocellular Carcinoma Experimental Models for TGF-β Promoting Tumor Progression" Cancers, 2019, 11, 1510; doi:10.3390/cancers11101510.109) Abdel-Majeed Safer, Stefano Leporatti, Jacquilion Jose, Mahmoud S. Soliman "Conjugation of EGCG and Chitosan NPs as a novel Nano-Drug Delivery System" International Journal of Nanomedicine 2019:14 8033–8046. (Awarded by University of Kuwait)
110) Stefano Leporatti (Ed.) ”Polymer Clay Nano-Composites" Pages: 246, Published: October 2019 ( This book is a printed edition of the Special Issue “Polymer Clay Nano-Composites” that was published in Polymers)

Call: FP7-PEOPLE-2012-ITN Marie Curie Initial Training Networks (ITN) "Strategy to Inihibit TGF-β1 in liver disease (IT-Liver)“ (2012-2016) Coordinator: Dr. Isabel Fabregat, PhD; CNR-Nano Responsable: Dr. Stefano Leporatti.